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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin, alpha 4 (Integrin alpha IV, Integrin alpha-4, IA4, ITGA4, CD49 Antigen-like Family Member D, CD49d, MGC90518, VLA-4 Subunit alpha, VLA4)

Anti -Integrin, alpha 4 (Integrin alpha IV, Integrin alpha-4, IA4, ITGA4, CD49
Antigen-like Family Member D, CD49d, MGC90518, VLA-4 Subunit alpha, VLA4)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
ITGA4s are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. It belongs to the integrin alpha chain family of proteins. The gene of this protein encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. CD14 is a novel ligand for alpha4beta1, exhibiting similar activation-state dependent binding characteristics as other alpha4beta1 ligands.
Catalog #I7661-34P
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlThymus, medulla
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the internal domain of human ITGA4.
SpecificityRecognizes human ITGA4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesIntegrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor)


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