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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49)

Anti -Integrin alpha5, beta1 (VLA5, Fibronectin Receptor, Very Late Antigen, CD49)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP FC
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Catalog #I7661-35R
ApplicationsSuitable for use in Immunoprecipitation and Flow Cytometry. Not suitable for use in Western Blot. Other applications have not been tested.
Recommended DilutionsImmunoprecipitation: 2ug to immunoprecipitate 10e6 cells from lysate.
Flow Cytometry: 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No2Q964
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
SpecificityRecognizes the fibronectin receptor VLA-5 (alpha5beta1) integrin complex. Species Crossreactivity: human and porcine
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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