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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin beta-1/CD29 (ITGB1, FNRB, MDF2, MSK12, Integrin beta-1, Fibronectin Receptor Subunit beta, Integrin VLA-4 Subunit beta)

Anti -Integrin beta-1/CD29 (ITGB1, FNRB, MDF2, MSK12, Integrin beta-1, Fibronectin
Receptor Subunit beta, Integrin VLA-4 Subunit beta)


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Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH FC
Integrin beta-1 (ITGB1, CD29, VLA-beta) is the beta subunit found in the integrin families, forming a heterodimer integrin receptor through non-covalent bonding with various integrin alpha subunits. Integrin heterodimer containing Integrin beta-1 binds to various cell surface and extracellular proteins (CD49a-f, CD51) to mediate cell to cell and cell to matrix adhesion (1). Integrin beta-1 plays a critical role in the cell adhesion and recognition in embryogenesis, hemostasis, immune response, tissue repair, metastatic diffusion of tumor cells and development (2, 3, 4).
Catalog #I7661-38S
ApplicationsSuitable for use in Flow Cytometry, Western Blot and Immunohistochemistry (paraffin). Not suitable for ICC/IF and IP. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:100 -1:1,000
Western Blot: 1:500. Detects a band of ~140-150kD (predicted MW: 88kD).
Immunohistochemistry: 1:100-250. Antigen retrieval required.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR1040Y
ConcentrationNot determined.
FormSupplied as a liquid (tissue culture supernatant), pH 7.4, containing 0.05% BSA, 0.01% sodium azide, and 50% glycerol.
ImmunogenSynthetic peptide corresponding to the residues in human Integrin beta-1 (CD29)
SpecificityRecognizes human Integrin beta-1 (CD29).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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