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Anti -ITGB1BP1 (ICAP1, Integrin beta-1-binding Protein 1, Integrin Cytoplasmic Domain-associated Protein 1, ICAP-1)
Anti -ITGB1BP1 (ICAP1, Integrin beta-1-binding Protein 1, Integrin Cytoplasmic
Domain-associated Protein 1, ICAP-1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E IH |
|
| ITGB1BP1 (Integrin beta 1 binding protein 1) binds to the beta 1 integrin cytoplasmic domain and negatively regulates its function in vitro. It may play a role in the recruitment of beta 1 integrins to the focal contacts during integrin-dependent cell adhesion. ITGB1BP1 shuttles between the nucleus and cytoplasm in a beta 1 integrin-dependent manner. It may act as a messenger that relays information from sites of integrin-dependent cell adhesion to the nucleus for controlling gene expression and cell proliferation. There are two alternatively spliced isoforms of ITGB1BP1. The shorter isoform does not interact with the beta 1 integrin cytoplasmic domain. | | | Catalog # | I7661-38X | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.2% gelatin, 0.02% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa92-105 of human ITGB1BP1 (KLH). | | Specificity | Recognizes human ITGB1BP1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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