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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin, beta1 (Integrin beta-1, ITGB1, CD29, Fibronectin Receptor Subunit beta, FNRB, GPIIA, MDF2, MSK12, VLA-4 Subunit beta, VLA-beta, VLAB)

Anti -Integrin, beta1 (Integrin beta-1, ITGB1, CD29, Fibronectin Receptor Subunit beta,
FNRB, GPIIA, MDF2, MSK12, VLA-4 Subunit beta, VLA-beta, VLAB)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
ITGB1 encodes the protein beta subunit. Integrins are heterodimers of two transmembrane chains, a and b. The b1 subunit is widely expressed and heterodimerize with at least 12 different subunits, generating integrins with differing ligand specificities. Integrins containing the b1 subunit regulate epidermal stem cell maintenance. Six alternatively spliced variants have been found for ITGB1 which encodes five proteins with alternate carboxy termini, Beta-1A, Beta-1B, Beta-1C, Beta-1C-2 and Beta-1D. Isoform beta-1A is widely expressed. Isoform beta-1B is expressed in skin, liver and skeletal muscle. Isoform beta-1C and isoform beta-1C-2 are expressed in muscle, kidney, liver and placenta. Isoform beta-1D is expressed specifically in striated muscle (skeletal and cardiac muscle). It is localized to Human chromosome 10p11.2.
Catalog #I7661-39R
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlSkin
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the Extracellular domain of human ITGB1.
SpecificityRecognizes human ITGB1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesIntegrin, beta 1 (Fibronectin Receptor, beta Polypeptide, Antigen CD29 Includes MDF2, MSK12)


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