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Anti -Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla)
Anti -Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IP IH IC FC RIA |
|
| CD29 is the integrin B1 chain which is expressed as heterodimer non-covalently associated with the integrin subunits 1 to 6 (CD49a to CD49f) and known as very late antigens (VLA). It is also called platelet GPlla. It has been reported as receptor of bronectin. The antigen mediates cellular adhesion primarily to collagen, laminin or fibronectin. It has a broad cellular reactivity but is not expressed by erythrocytes. In normal peripheral blood CD29 blood CD29 is found on approximately 41% of T cells, 40% of CD4+ T lymphocytes, 43% of CD8+ T lymphocytes (1). It is slightly reactive with peripheral B-cells. The co-expression of CD4 and CD29 allows the identi cation of the helper/inducer subpopulation of CD4 lymphocytes. | | | Catalog # | I7661-39T | | Applications | Suitable for use in RIA, Flow Cytometry, ELISA, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry, Functional blocking. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: acetone fixation, not suitable for paraffin embedded. | | Immunocytochemistry: paraformaldehyde fixation at <4% | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 2Q847 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 0.02M PBS, pH 7.6, 0.1% sodium azide. | | Purity | Purified by Protein A chromatography | | Immunogen | Human keratinocytes derived from skin. | | Specificity | Recognizes human Integrin beta 1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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