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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla)

Anti -Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IP IH IC FC RIA
CD29 is the integrin B1 chain which is expressed as heterodimer non-covalently associated with the integrin subunits 1 to 6 (CD49a to CD49f) and known as very late antigens (VLA). It is also called platelet GPlla. It has been reported as receptor of bronectin. The antigen mediates cellular adhesion primarily to collagen, laminin or fibronectin. It has a broad cellular reactivity but is not expressed by erythrocytes. In normal peripheral blood CD29 blood CD29 is found on approximately 41% of T cells, 40% of CD4+ T lymphocytes, 43% of CD8+ T lymphocytes (1). It is slightly reactive with peripheral B-cells. The co-expression of CD4 and CD29 allows the identi cation of the helper/inducer subpopulation of CD4 lymphocytes.
Catalog #I7661-39T
ApplicationsSuitable for use in RIA, Flow Cytometry, ELISA, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry, Functional blocking. Other applications not tested.
Recommended DilutionImmunohistochemistry: acetone fixation, not suitable for paraffin embedded.
Immunocytochemistry: paraformaldehyde fixation at <4%
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q847
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.02M PBS, pH 7.6, 0.1% sodium azide.
PurityPurified by Protein A chromatography
ImmunogenHuman keratinocytes derived from skin.
SpecificityRecognizes human Integrin beta 1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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