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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin, beta 3 (ITGB3, CD61, GP3A, GPIIIa, HPA-1, NAIT, Platelet Fibrinogen Receptor beta Subunit, Platelet Glycoprotein IIIa, Platelet Membrane Glycoprotein IIIa)

Anti -Integrin, beta 3 (ITGB3, CD61, GP3A, GPIIIa, HPA-1, NAIT, Platelet Fibrinogen
Receptor beta Subunit, Platelet Glycoprotein IIIa, Platelet Membrane Glycoprotein IIIa)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
CD61, a 105kD membrane glycoprotein, is a member of Integrin family expressed on megakaryocytes, platelets and their precursor cells. It is a beta3-integrin subunit consisting of an N-terminal signal peptide, a transmembrane domain and a cysteine-rich cytoplasmic domain. CD61 is a functional subunit of platelet integrin GPIIb:IIIa receptor complex, fibronectin receptor and Vitronectin receptor. It mediates platelet aggregation, platelet spreading, clot retraction, microvesiculation, and hemostasis and also functions as a receptor for fibrinogen, fibronectin, Von Willebrand factor, Osteopontin and Vitronectin.
Catalog #I7661-42F2
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 1:25-1:50
Optimal dilutions to be determined by the researcher.
Positive ControlHuman bone marrow
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11E232
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide.
PuritySupernatant
ImmunogenPHA-stimulated human mononuclear cells. Cellular Localization: Cell membrane.
SpecificityRecognizes human CD61.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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