b3-Integrins contain receptors for vitronectin, fibrinogen, and Von Willebrands factor and, in some instances fibronectin. The b3-Integrin subunit is a common subunit protein for this integrin family. The aIIb-Integrin subunit is a specific marker for platelets and megakaryocytes and can be utilized for this purpose in various immunological techniques. Monoclonal antibodies against the b3-Integrin subunits and the aIIb-Integrin subunit can be used in immunoblotting, immunoprecipitation and immunostaining experiments.
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