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You are here:Home » Antibodies » Abs to Integrin » Anti -Integrin beta6

Anti -Integrin beta6

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH IC FC
Integrins are a large family of transmembrane proteins composed of an alpha and beta component. Integrins are involved in a diversity of biological functions such as cell adhesion, structure, differentiation, apoptosis and cell proliferation. They are the principal cell surface receptors that recognise cell to matrix interactions but little is known about the expression of beta 1 integrin family on airway smooth muscle (ASM) and their involvement in proliferation. This is a contributing factor in structural changes seen in asthma.
Catalog #I7661-44A
ApplicationsSuitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Not suitable for use in Function Blocking or Western Blot. Other applications not tested.
Recommended DilutionsImmunoprecipitation: Because I7661-44A is an IgG2a, protein G or rabbit anti-mouse IgG is helpful for capture.
Immunohistochemistry(IC): Acetone fix. Nuclear background staining limits usefulness in these techniques.
Otimal dilution to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No2Q791
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS. No preservatives added.
PurityPurified by affinity chromatography.
ImmunogenMurine NIH 3T3 cells stably transfected with the human b6 subunit.
SpecificityRecognizes human Integrin beta6.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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