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Anti -Integrin beta-like 1 with EGF-like Repeat Domains (ITGBL1)
Anti -Integrin beta-like 1 with EGF-like Repeat Domains (ITGBL1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Chicken |
Affinity Purified |
E B IH IC |
|
| By screening an EST cDNA database for sequence homology with integrins, Berg et al. (1999) identified overlapping partial-length cDNA clones from human osteoclastoma, fetal lung, and umbilical vein endothelial cDNA libraries. A subsequent screening identified a potential full-length clone from an osteoblast cell cDNA library. The novel cDNA clone was found to encode a 494-amino acid protein, which the authors designated TIED (ten beta-integrin EGF-like repeat domains). The sequence comprised a typical signal peptide, followed by a hydrophilic 471-amino acid domain containing 10 tandem EGF-like repeats strikingly similar to those found in the cysteine-rich 'stalk-like' structure of integrin-beta subunits. Northern blot analysis revealed a single RNA transcript of approximately 2.8 kb. TIED was widely expressed in many tissues, but readily detectable only in aorta. | | | Catalog # | I7661-49 | | Applications | Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:250 | | Immunohistochemistry: 1:100 | | Immunocytochemistry: 1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgY | | Host | Chicken | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa242-291 of ITGBL1. | | Specificity | Recognizes human ITGBL1 (Integrin beta-like 1 with EGF-like Repeat Domains) | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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