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Interferon alpha 2b, aa24-188, Recombinant, Human (IFNa2, IFNa2b)
Interferon alpha 2b, aa24-188, Recombinant, Human (IFNa2, IFNa2b)
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| Interferon induces a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. Interferon a-2b can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon a-2b was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. | | | Catalog # | I7661-75B | | Recombinant protein corresponding to aa24-188 of human IFNA2 expressed in E. coli (NP_000596). | | AA Sequence | MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 19.4kD | | Source | E. coli | | Purity | 95% (SDS-PAGE) | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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