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You are here:Home » Antibodies » Abs to Interferon » Anti -Interferon alpha Receptor 1, phosphorylated (Ser535/Ser539) (Interferon alpha/beta Receptor 1, IFN-alpha/beta Receptor 1, IFNAR1, IFNAR, IFNBR, IFN-R-1, AVP, Cytokine Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, CRF2-1, IFRC, IFN-alpha

Anti -Interferon alpha Receptor 1, phosphorylated (Ser535/Ser539) (Interferon alpha/beta
Receptor 1, IFN-alpha/beta Receptor 1, IFNAR1, IFNAR, IFNBR, IFN-R-1, AVP, Cytokine
Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, CRF2-1, IFRC, IFN-alpha

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the type 1 interferon receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Catalog #I7661-76T5
ApplicationsSuitable for use in Western Blot.. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlHuman brain
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 10mM HEPES (pH 7.5), 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to amino acid residues surrounding the human IFNAR1 phosphorylated (Ser535/539).
SpecificityRecognizes human Interferon Receptor, Type I, Subunit I, phosphorylated at (Ser535/539). Species crossreactivity: bovine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesInterferon (alpha, beta and omega) Receptor 1


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