Anti -Interferon alpha Receptor 1, phosphorylated (Ser535/Ser539) (Interferon alpha/beta
Receptor 1, IFN-alpha/beta Receptor 1, IFNAR1, IFNAR, IFNBR, IFN-R-1, AVP, Cytokine
Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, CRF2-1, IFRC, IFN-alpha
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the type 1 interferon receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1. | | | Catalog # | I7661-76T5 | | Applications | Suitable for use in Western Blot.. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human brain | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 10mM HEPES (pH 7.5), 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to amino acid residues surrounding the human IFNAR1 phosphorylated (Ser535/539). | | Specificity | Recognizes human Interferon Receptor, Type I, Subunit I, phosphorylated at (Ser535/539). Species crossreactivity: bovine, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Interferon (alpha, beta and omega) Receptor 1 |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -Interferon alpha Receptor 1, phosphorylated (Ser535/Ser539) (Interferon alpha/beta Receptor 1, IFN-alpha/beta Receptor 1, IFNAR1, IFNAR, IFNBR, IFN-R-1, AVP, Cytokine Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, CRF2-1, IFRC, IFN-alpha |
External Links
|
