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You are here:Home » Antibodies » Abs to Interferon » Anti -Interferon, beta, neutralizing (Interferon beta, IFN-beta, Fibroblast Interferon, IFB, IFNB)

Anti -Interferon, beta, neutralizing (Interferon beta, IFN-beta, Fibroblast Interferon,
IFB, IFNB)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B IP IH N
interferon beta (IFN Beta), a 22kD cytokine with wide-ranging antiviral, antimicrobial and antitumor effects. Interferons also serve to activate macrophages, natural killer cells and the presentation of antigens to the immune system by the major histocompatibility complex. The production of interferon is induced in response to microbes and other cytokines. The interferons are widely used to treat a variety of diseases and IFNB in particular is used to treat relapsing-remitting multiple sclerosis.
Catalog #I7662-10N
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Neutralization. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Biological Activity2 x 10e4 Units at 1.12 x 10e5 Neutralization Units/ml.
Unit DefinitionOne neutralization unit is the amount of antiserum required to neutralize 1 unit of mouse IFN-beta. This material is prepared specifically for effective neutralization of mouse IFN-beta.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationNot determined.
FormSupplied as a liquid.
PuritySerum
ImmunogenLinear peptide corresponding to the internal domain of mouse Interferon beta, conjugated to KLH.
SpecificityRecognizes mouse IFN-b at ~18kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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