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Interferon beta, Recombinant, Mouse, aa22-182, His-tag (Ifb, IFN-beta, IFNB)
Interferon beta, Recombinant, Mouse, aa22-182, His-tag (Ifb, IFN-beta, IFNB)
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| Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis. | | | Catalog # | I7662-11C | | Source | Recombinant corresponding to aa22-182 from mouse Interferon beta expressed in E. coli. | | Molecular Weight | 22.0kD (182aa) | | | | AA Sequence: | | MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN | | Storage and Stability | Aliquot to avoid repeated freezing and thawing and Store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Molecular Weight | 22.0kD | | Source | His-tagged, Recombinant, E. coli | | Purity | 95% (SDS-PAGE) | | Concentration | ~0.5mg/ml | | Form | Supplied as liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 30% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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