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Anti -Interferon gamma, neutralizing (IFNg)
Anti -Interferon gamma, neutralizing (IFNg)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E N |
|
| Interferon gamma is the only known type II interferon. Under physiological conditions, interferon gamma is induced when T-lymphocytes, previously sensitized to an antigen, are exposed to the same antigen, hence its other name: immune interferon. Interferon gamma has demonstrated significant anti-proliferative effects in in vivo studies; however, its therapeutic effects have been limited. Endogenous IFN-g has been shown to be required for the protection of mice against mycobacteri and leishmaniasis. In the U.S., human IFN-g has been approved for reducing the frequency and severity of infections in patients with chronic granulomatous disease. | | | Catalog # | I7662-15A1 | | Applications | Suitable for use as a neutralizing and binding (ELISA) antibody. This antibody only works in a capture ELISA assay. It does not recognize plastic-bound IFN-gamma, but works very well in capture ELISA when used as the first, plastic bound antibody (and then developed with polyclonal antibody). | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9L376 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as lyophilized powder from PBS. Reconstitute with 0.2ml water. | | Purity | Purified by Protein A/S-Sepharose. | | Immunogen | Recombinant human INF-gamma. | | Specificity | Recognizes human Interferon gamma. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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