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You are here:Home » Antibodies » Abs to Interferon » Anti -Interferon gamma, neutralizing (IFNg)

Anti -Interferon gamma, neutralizing (IFNg)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E N
Interferon gamma is the only known type II interferon. Under physiological conditions, interferon gamma is induced when T-lymphocytes, previously sensitized to an antigen, are exposed to the same antigen, hence its other name: immune interferon. Interferon gamma has demonstrated significant anti-proliferative effects in in vivo studies; however, its therapeutic effects have been limited. Endogenous IFN-g has been shown to be required for the protection of mice against mycobacteri and leishmaniasis. In the U.S., human IFN-g has been approved for reducing the frequency and severity of infections in patients with chronic granulomatous disease.
Catalog #I7662-15A1
ApplicationsSuitable for use as a neutralizing and binding (ELISA) antibody. This antibody only works in a capture ELISA assay. It does not recognize plastic-bound IFN-gamma, but works very well in capture ELISA when used as the first, plastic bound antibody (and then developed with polyclonal antibody).
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9L376
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as lyophilized powder from PBS. Reconstitute with 0.2ml water.
PurityPurified by Protein A/S-Sepharose.
ImmunogenRecombinant human INF-gamma.
SpecificityRecognizes human Interferon gamma.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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