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You are here:Home » Antibodies » Abs to Interferon » Anti -Interferon, gamma (IFNg) (Biotin)

Anti -Interferon, gamma (IFNg) (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E
Interferon-gamma (IFN-gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
Catalog #I7662-18X
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsELISA (Detection): 0.1-1ug/ml. Dilutions should be made in a buffer appropriate for use in ELISA, such as PBS supplemented with 0.5% BSA, 0.1% Tween-20.
Optimal dilutions to be determined by the researcher.
HybridomaBalb/c (Charles River) / Sp2/O Ag14
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2B2.115
HostMouse
SourcePorcine
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Labeled with Biotin.
PurityPurified
ImmunogenRecombinant porcine IFN-g
SpecificityRecognizes natural and recombinant porcine IFN-g.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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