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You are here:Home » Growth Factors, Cytokines » Growth Factors-I-TAC » Interferon-inducible T Cell Alpha Chemoattractant, Murine (I-TAC)

Interferon-inducible T Cell Alpha Chemoattractant, Murine (I-TAC)

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Specifications

Murine Interferon-inducible T cell alpha chemoattractant (I-TAC) is a novel non-ELR CXC chemokine. Murine I-TAC is regulated by interferon and has potent chemoattractant activity for IL-2 activated T cells, but not for freshly isolated unstimulated T cells, neutrophils, or monocytes. Recombinant Murine I-TAC is a 9kD protein containing 79 amino acid residues.
Catalog #I7662-19C
SourceE.coli
FormSterile filtered and lyophilized without additives.
StabilityLyophilized protein, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted I-TAC should be stored in working aliquots at-20°C.
Purity 98% by SDS-PAGE and HPLC analysis.
Endotoxin 0.1ng/ug (1EU/ug)
ReconstitutionLyophilized human I-TAC is soluble in water and most aqueous buffers and can be reconstituted in water to a concentration of 0.11.0mg/ml. This solution can be diluted into other buffered solutions or stored frozen for future use.
Biological Activity Determined by its ability to chemoattract murine CXCR3 transfected HEK/293 cells using a concentration range of 10-100ng/ml.
AA Sequence FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRKQNM
Country of Origin USA
Molecular Weight9.0kD
SourceHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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