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You are here:Home » Antibodies » Abs to Interferon » Anti -IRF2 (IRF-2, Interferon Regulatory Factor 2)

Anti -IRF2 (IRF-2, Interferon Regulatory Factor 2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
Catalog #I7662-79F
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:2000
Western Blot: 1-3ug/ml, lysates of cell line Jurkat observed on ~48kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to KTSDITQARVKSC, from IRF2, at C-terminal (NP_002190.2).
SpecificityRecognizes human IRF2. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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