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Interferon Regulatory Factor 1, Recombinant, Human (IRF1)
Interferon Regulatory Factor 1, Recombinant, Human (IRF1)
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| IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-alpha, IFN-beta, and IFN-gamma stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines. Recombinant human IRF1 was expressed in E. coli and purified by using conventional chromatography techniques. | | | Catalog # | I7662-81 | | Molecular Weight | 15kD (114 amino acids) | | Sequences | MGSSHHHHHH/ SSGLVPRGSH/ MPITRMRMRP/ WLEMQINSNQ/ IPGLIWINKE/ EMIFQIPWKH/ AAKHGWDINK/ DACLFRSWAI/ HTGRYKAGEK/ EPDPKTWKAN/ FRCAMNSLPD/ IEEVKDQSRN/ KGSSAVRVYR/ MLPP | | | | Storage and Stability: | | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 15kD | | Source | Recombinant, Human, His-tag, E. coli | | Purity | 90% by SDS-PAGE | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris, pH 8.0, 10% glycerol | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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