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You are here:Home » Antibodies » Abs to Interferon » Anti -Interferon Regulatory Factor 6 (IRF6)

Anti -Interferon Regulatory Factor 6 (IRF6)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
Catalog #I7662-89Q
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:1:32,000
Immunohistochemistry: 2-3ug/ml in paraffin embedded Human Kidney shows strong nuclear staining in DCT and glomerulus
Western Blot: 0.2-0.6ug/ml; ~60kD band observed in Human Ovary lysates (calculated MW of 53.1kD according to NP_006138.1). In transfected HEK293 transiently expressing IRF6 a band of approx. 55kD is observed. This band is not observed in the non-transfected HEK293
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-TPSMQLPPALPPQ, from the C Terminus of human IRF6 (NP_006138.1).
SpecificityRecognizes human IRF6. Species sequence homology: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesOFC6, VWS, PPS, PIT, LPS, interferon regulatory factor 6, IRF6


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