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Anti -Interferon Regulatory Factor 8 (IRF8, ICSBP1, Interferon Consensus Sequence Binding Protein 1, HGNC5358, MYLS)
Anti -Interferon Regulatory Factor 8 (IRF8, ICSBP1, Interferon Consensus Sequence Binding
Protein 1, HGNC5358, MYLS)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Interferon regulatory factor 8, (IRF8) also known as Interferon consensus sequence-binding protein (ICSBP). It is part of a transcriptional network that governs B cell lineage specification, commitment and differentiation. It is expressed in T cells, B cells and macrophages. Macrophage, dendritic and B cell development is impaired in IRF deficient mice. IRF8 appears to play a negative regulatory role in IFN induction of genes in most cases. | | | Catalog # | I7662-93D | | Applications | Suitable for use in Western Blot Other applications not tested. | | Recommended Dilution | Westen Blot: 1-2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to 16aa near the carboxy terminus of human IRF8. | | Specificity | Recognizes human interferon regulatory factor 8. Species Cross Reactivity: mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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