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Anti -Interleukin 1 alpha (IL-1a, IL-1 alpha, Hematopoietin 1, H1, IL-1F1, Preinterleukin 1 alpha, Pro interleukin 1 alpha)
Anti -Interleukin 1 alpha (IL-1a, IL-1 alpha, Hematopoietin 1, H1, IL-1F1, Preinterleukin
1 alpha, Pro interleukin 1 alpha)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. | | | Catalog # | I7663-03C | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 8L420 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | As reported | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Ni-NTA purified recombinant human IL-1?#193; expressed in E. Coli strain BL21 (DE3). | | Specificity | Species Crossreactivity: Human. Other species have not been tested | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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