Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 1 alpha (IL-1a) (Biotin)

Anti -Interleukin 1 alpha (IL-1a) (Biotin)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Catalog #I7663-07
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: (as a detection antibody): 0.1-1ug/ml. Dilutions should be made in buffered solution containing a carrier protein (e.g., 0.1%-1.0% BSA). A preservative, such as 0.1% sodium azide, may also be added.
Optimal dilutions to be determined by the researcher.
HybridomaBALB/c mouse splenocytes were fused with NSO mouse myeloma cells.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No2B2.116
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.5, 0.5% BSA, and 0.05% sodium azide. Labeled with Biotin.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant human IL-1a.
SpecificityRecognizes natural and recombinant human IL-1a.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links