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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 1 beta (IL1b, IL-1 beta, Catabolin, Hematopoietin 1, H1, IFN beta Inducing Factor, IL1F2, LAF, OAF, Osteoclast Activating Factor, Preinterleukin beta, Pro Interleukin 1 beta) (Azide Free)

Anti -Interleukin 1 beta (IL1b, IL-1 beta, Catabolin, Hematopoietin 1, H1, IFN beta
Inducing Factor, IL1F2, LAF, OAF, Osteoclast Activating Factor, Preinterleukin beta, Pro
Interleukin 1 beta) (Azide Free)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
IL1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of
acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen
induction. The previous names by which IL1
has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin1,
melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression. Studies using chicken models have indicated physiological similarities between chIL1beta and mammalian IL1beta in relation to its neural distribution and several factors have been shown to induce chIL1beta secretion, including protein kinase C (PKC), Calmodulindependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica.
Catalog #I7663-08V
ApplicationsSuitable for use in ELISA, Functional Assays and Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: Detects a band at ~29kD in HD-11 cell lysates transfected with chIL-1.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceChicken
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS. No preservative added (Azide free).
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to chicken IL1.
SpecificityRecognizes and neutralizes chicken IL-1 beta.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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