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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 1 beta (IL-1b)

Anti -Interleukin 1 beta (IL-1b)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Interleukin 1 beta (IL-1b) and Interleukin 1 alpha (IL-1a) have very similar biological activities on many different cell types although they are derived from different genes and share only ~20% aa sequence homology. IL-1b is synthesized as pro-IL-1b in cells and is cleaved to produce active IL-1b by Interleukin-1b converting enzyme (ICE), a cytoplasmic cysteine protease which is also known as caspase-1.
Catalog #I7663-09C
ApplicationsSuitable for use in Western Blot. The antibody is not neutralizing when tested in a proliferation assay. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourcePorcine
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2. No preservative added.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant porcine IL-1b.
SpecificityRecognizes porcine IL-1b. Does not react with porcine IL-1a.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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