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Specifications

Clone Host Grade Applications Monoclonal Mouse Highly Purified E

Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also from several other cell types. It is thought to play a key role in inflammatory and immune responses. These two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta), bind to the same cell surface receptor and elicit nearly identical biological responses. Their amino acid sequences also and share 25% homology.
Catalog #	I7663-11T
Applications	Suitable for use in ELISA. Other applications not tested.
Recommended Dilution	ELISA: 1:20,000
	Optimal dilutions to be determined by the researcher.
Storage and Stability	Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2b
Clone No	8A186
Host	Mouse
Source	Human
Concentration	~1mg/ml
Form	Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH2O.
Purity	Purified by ion exchange chromatography.
Immunogen	Recombinant human IL-1b
Specificity	Recognizes human IL-1 beta.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.