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Interleukin 1 beta, Recombinant, Mouse (IL-1b)
Interleukin 1 beta, Recombinant, Mouse (IL-1b)
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| Interleukin-1 beta (IL-1beta) is a potent immunomodulator which mediates a wide range of immune and inflammatory responses, including the activation of B and T cells. Murine IL-1b is a 17.5kD protein containing 153 amino acid residues. | | | Catalog # | I7663-22 | | Biological Activity | Murine IL-1b is fully biologically active when compared to standards. The ED50 as determined by the dose-dependent stimulation of murine D10S cells is 0.002ng/ml, corresponding to a specific activity of 5x10e8 units/mg. | | Responding Cells (partial list) | Leukocytes. | | AA Sequence | MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O containing a carrier protein. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 17.5kD | | Source | Murine, recombinant, produced in E. coli | | Purity | ~ 98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug | | Form | Supplied as a lyophilized powder from sodium citrate, pH 4.0. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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