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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 1 Receptor Type I (Interleukin Receptor 1, IL-1R-1, IL1R1, IL-1RT1, IL1RT1, Interleukin 1 Receptor alpha Type 1, IL-1R alpha, IL1RA, Antigen CD121a, CD121A, CD121a Antigen, D2S1473, IL-1R1, IL1 Inhibitor, P80) (APC)

Anti -Interleukin 1 Receptor Type I (Interleukin Receptor 1, IL-1R-1, IL1R1, IL-1RT1,
IL1RT1, Interleukin 1 Receptor alpha Type 1, IL-1R alpha, IL1RA, Antigen CD121a, CD121A,
CD121a Antigen, D2S1473, IL-1R1, IL1 Inhibitor, P80) (APC)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B FC
Two distinct receptors bind the pleiotropic cytokines IL-1a and IL-1b. The IL-1 Receptor I (IL-1 RI) is an 80kD transmembrane protein expressed predominantly in T cells, fibroblasts, and endothelial cells. IL-1 Receptor II is a 68kD protein that is found on B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Both receptors are members of the immunoglobulin superfamily and show ~28% sequence identity in their extracellular domains. The two receptors do not heterodimerize into a receptor complex. Soluble recombinant IL-1 Receptor I is a potent antagonist of IL-1 action.
Catalog #I7663-25C5
ApplicationsSuitable for use in ELISA, Western Blot and Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul/10e6 HUVEC human umbilical vein endothelial cells
Optimal dilutions to be determined by the researcher.
Absorption 620-650nm
Emission 660-670nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein corresponding to human IL-1 RI extracellular domain expressed in Sf-21 cells.
SpecificityRecognizes human IL-1 RI.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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