Anti -Interleukin 1 Receptor Type I (Interleukin Receptor 1, IL-1R-1, IL1R1, IL-1RT1,
IL1RT1, Interleukin 1 Receptor alpha Type 1, IL-1R alpha, IL1RA, Antigen CD121a, CD121A,
CD121a Antigen, D2S1473, IL-1R1, IL1 Inhibitor, P80) (APC)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
FC |
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| Two distinct receptors bind the pleiotropic cytokines IL-1a and IL-1b. The IL-1 Receptor I (IL-1 RI) is an 80kD transmembrane protein expressed predominantly in T cells, fibroblasts, and endothelial cells. IL-1 Receptor II is a 68kD protein that is found on B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Both receptors are members of the immunoglobulin superfamily and show ~28% sequence identity in their extracellular domains. The two receptors do not heterodimerize into a receptor complex. Soluble recombinant IL-1 Receptor I is a potent antagonist of IL-1 action. | | | Catalog # | I7663-25C5 | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Absorption | 620-650nm | | Emission | 660-670nm | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in PBS, 1ml saline, 0.5% BSA, and 0.1% sodium azide. Labeled with Allophycocyanin (APC). | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to human IL-1 RI extracellular domain expressed in Sf-21 cells. | | Specificity | Recognizes human IL-1 RI. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Interleukin 1 Receptor Type I (Interleukin Receptor 1, IL-1R-1, IL1R1, IL-1RT1, IL1RT1, Interleukin 1 Receptor alpha Type 1, IL-1R alpha, IL1RA, Antigen CD121a, CD121A, CD121a Antigen, D2S1473, IL-1R1, IL1 Inhibitor, P80) (APC) |
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