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You are here:Home » Antibodies » Abs to Interleukin » Anti -IL1R1 (Interleukin-1 Receptor Type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 Antigen-like Family Member A, Interleukin-1 Receptor alpha, IL-1R-alpha, Interleukin-1 Receptor Type I, p80, CD121a, IL1R, IL1RA, IL1RT1)

Anti -IL1R1 (Interleukin-1 Receptor Type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 Antigen-like
Family Member A, Interleukin-1 Receptor alpha, IL-1R-alpha, Interleukin-1 Receptor Type I,
p80, CD121a, IL1R, IL1RA, IL1RT1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH RIA
CD121a is the 80kD type I interleukin-1 receptor. CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a.
Catalog #I7663-25D3
ApplicationsSuitable for use in RIA, ELISA and Immunohistochemistry. Not suitable for use in Western Blot. Other applications not tested.
Recommended DilutionsImmunohistochemistry (FFPE): 10ug/ml. Validated for use on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with I7663-25D3, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
RIA: 20-30ng/ml
ELISA: 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4.
PurityPurified by Protein G affinity chromatography.
ImmunogenExtracellular domain of the type I human IL1R1.
SpecificityRecognizes human IL1R1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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