Anti -IL1R1 (Interleukin-1 Receptor Type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 Antigen-like Family Member A, Interleukin-1 Receptor alpha, IL-1R-alpha, Interleukin-1 Receptor Type I, p80, CD121a, IL1R, IL1RA, IL1RT1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH RIA |
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| CD121a is the 80kD type I interleukin-1 receptor. CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a. | | | Catalog # | I7663-25D3 | | Applications | Suitable for use in RIA, ELISA and Immunohistochemistry. Not suitable for use in Western Blot. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (FFPE): 10ug/ml. Validated for use on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with I7663-25D3, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. | | RIA: 20-30ng/ml | | ELISA: 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Monoclonal | | Isotype | IgG2b | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Extracellular domain of the type I human IL1R1. | | Specificity | Recognizes human IL1R1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -IL1R1 (Interleukin-1 Receptor Type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 Antigen-like Family Member A, Interleukin-1 Receptor alpha, IL-1R-alpha, Interleukin-1 Receptor Type I, p80, CD121a, IL1R, IL1RA, IL1RT1) |
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