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You are here:Home » Antibodies » Antibodies-Interleukin » Anti -Interleukin 1 Receptor Type II (IL-1RII, IL1R2, IL-1R2, IL-1R-2, IL-1RT2, IL-1RT-2, CD121 Antigen-like Family Member B, CD121b, CDw121B, Interleukin-1 Receptor beta, IL-1R beta, IL-1R-beta, IL1RB, IL1-Rb, MGC47725) (APC)

Anti -Interleukin 1 Receptor Type II (IL-1RII, IL1R2, IL-1R2, IL-1R-2, IL-1RT2, IL-1RT-2,
CD121 Antigen-like Family Member B, CD121b, CDw121B, Interleukin-1 Receptor beta, IL-1R
beta, IL-1R-beta, IL1RB, IL1-Rb, MGC47725) (APC)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Interleukin-1 receptor II (IL-1 RII), also known as CD121b, is an immunoglobulin superfamily receptor that binds the pleiotropic cytokines IL-1a and IL-1b. It acts as an IL-1 antagonist because it has a short cytoplasmic domain and does not transduce IL-1 signals. IL-1 RII exists both as a transmembrane protein and as a soluble form that is released by proteolysis.
Catalog #I7663-25K8
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 10ul/10e6 cells using human peripheral blood mononuclear cells
Optimal dilutions to be determined by the researcher.
HybridomaMyeloma with B cells from Balb/c mice.
Storage and StabilityStore product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C25
HostMouse
SourceHuman
Concentration~0.01mg/ml
FormSupplied as a liquid in saline, <0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified, recombinant protein corresponding to aa14-343 of human IL-1R II (P27930), expressed in Sf 21 insect cell line.
SpecificityRecognizes human IL-1 RII.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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