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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 1 Receptor Type II (IL-1RII, IL1R2, IL-1R2, IL-1R-2, IL-1RT2, IL-1RT-2, CD121 Antigen-like Family Member B, CD121b, CDw121B, Interleukin-1 Receptor beta, IL-1R beta, IL-1R-beta, IL1RB, IL1-Rb, MGC47725) (APC)

Anti -Interleukin 1 Receptor Type II (IL-1RII, IL1R2, IL-1R2, IL-1R-2, IL-1RT2, IL-1RT-2,
CD121 Antigen-like Family Member B, CD121b, CDw121B, Interleukin-1 Receptor beta, IL-1R
beta, IL-1R-beta, IL1RB, IL1-Rb, MGC47725) (APC)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Interleukin-1 receptor II (IL-1 RII), also known as CD121b, is an immunoglobulin superfamily receptor that binds the pleiotropic cytokines IL-1a and IL-1b. It acts as an IL-1 antagonist because it has a short cytoplasmic domain and does not transduce IL-1 signals. IL-1 RII exists both as a transmembrane protein and as a soluble form that is released by proteolysis.
Catalog #I7663-25K8
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
HybridomaMyeloma with B cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing Allophycocyanin conjugates will result in a substantial loss of enzymatic activity.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C25
HostMouse
SourceHuman
Concentration~0.01mg/ml
FormSupplied as a liquid in sodium chloride, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by immunoaffinity chromatography.
ImmunogenPurified, insect cell line Sf 21-derived, recombinant human IL-1R II (aa14-343; Accession # P27930).
SpecificityRecognizes human IL-1 RII.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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