You are here:Home
»
Antibodies
»
Abs to Interleukin
»
Anti -Interleukin 1 Receptor AcP, C1 (Interleukin-1 Receptor Accessory Protein, IL-1 Receptor Accessory Protein, IL-1RAcP, IL1RAP, C3orf13, FLJ37788, Interleukin-1 Receptor 3, IL1R3, IL-1R3, IL-1R-3)
Anti -Interleukin 1 Receptor AcP, C1 (Interleukin-1 Receptor Accessory Protein, IL-1
Receptor Accessory Protein, IL-1RAcP, IL1RAP, C3orf13, FLJ37788, Interleukin-1 Receptor 3,
IL1R3, IL-1R3, IL-1R-3)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruites to the IL-1R complex through IL-1 RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues. | | | Catalog # | I7663-25Y | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:1000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | HeLa whole cell lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to human IL-1RAcP (CT) (NP_608273). | | Specificity | Recognizes human IL-1RAcP (C1). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -Interleukin 1 Receptor AcP, C1 (Interleukin-1 Receptor Accessory Protein, IL-1 Receptor Accessory Protein, IL-1RAcP, IL1RAP, C3orf13, FLJ37788, Interleukin-1 Receptor 3, IL1R3, IL-1R3, IL-1R-3) |
External Links
|
