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Interleukin 2, Recombinant, Human (Interleukin-2, IL-2, IL2, Aldesleukin, Lymphokine, T-cell Growth Factor, TCGF)
Interleukin 2, Recombinant, Human (Interleukin-2, IL-2, IL2, Aldesleukin, Lymphokine,
T-cell Growth Factor, TCGF)
Pricing
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| Interleukin-2 is a potent immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Human IL-2 is a 15.5kD protein containing 134 amino acid residues including one intrachain disulfide bond. | | | Catalog # | I7663-26 | | Biological Activity | The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is 0.1ng/ml, corresponding to a specific activity of 1x10e7u/mg. | | AA Sequence | MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with acetic acid. For long term storage add 0.1% carrier protein. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 15.5kD | | Source | E. coli | | Purity | 97% by SDS-PAGE and HPLC analyses. Endotoxin: 0.1ng/ug | | Form | Supplied as a lyophilized powder from 10mM sodium citrate, pH 4.0. Reconstitute in 100mM acetic acid to a concentration of 0.1-1.0mg/ml. For long term storage add 0.1% carrier protein. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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