Interleukin 2, Recombinant, Human (Interleukin-2, IL-2, IL2, Aldesleukin, Lymphokine,
T-cell Growth Factor, TCGF)
Pricing
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| Human IL-2 (also known as TCGF) is an about 15KD factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active. Recombinant human IL-2 is biologically active and can promote proliferation of T lymphocytes in culture. | | | Catalog # | I7663-26A5 | | Source | Escherichia coli. | | Biological Activity | Bioactivity is detected using WISH cell (a heteroploid human amnion cell line) as dependent cell strain. The specific activity shall be not less than 1.5×10e7 IU/mg of protein. | | Endotoxin | 1EU/ug (LAL) | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 1 month at 4 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~15.04kD | | Source | E. coli | | Purity | 97% as determined by SDS-PAGE and HPLC. | | Form | Supplied as a lyophilized powder from 0.2um sterile-filtered solution in PBS, pH 7.0, 50ug of HSA per 1ug of cytokine. Reconstitute with sterile, dH2O to 0.1mg/ml. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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