You are here:Home
»
Growth Factors, Cytokines
»
Growth Factors-Interleukin
»
Interleukin 2, Recombinant, Human (Interleukin-2, IL-2, IL2, Aldesleukin, Lymphokine, T-cell Growth Factor, TCGF)
Interleukin 2, Recombinant, Human (Interleukin-2, IL-2, IL2, Aldesleukin, Lymphokine,
T-cell Growth Factor, TCGF)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. | | | Catalog # | I7663-28A1 | | Recombinant Human IL-2 is a single non-glycosylated mutein (variant form) of human IL-2 polypeptide chain containing 134aa and having a molecular weight of 15.5kD. The sequence of the first five N-terminal aa was determined to be Met-Ala-Pro-Thr-Ser. Recombinant Human IL-2 has a Ser substitute for Cysteine at position 126. Molecular Weight | ~15.5kD | | Activity | The ED50 as determined by the dose-dependent stimulation of mouse CTLL-2 cells is less than 0.0645ng/ml, corresponding to a specific activity of 16.9MIU/mg. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Stable for at least 6 months at -20°C. Reconstitute with sterile deionized water to a concentration 100ug/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~15.5kD | | Source | E. coli | | Purity | 98% (RP-HPLC, SDS-PAGE). | | Form | Supplied as a lyophilized powder in PBS, pH 7.5. No preservative added. Reconstitute with 20mM acetic acid to a concentration 100ug/ml. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
