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You are here:Home » Antibodies » Abs to Interleukin » Anti -IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5 Receptor Common beta Subunit, CSF2RB, IL5RB)

Anti -IL3RB (CD131, Cytokine Receptor Common Subunit beta, CDw131, GM-CSF/IL-3/IL-5
Receptor Common beta Subunit, CSF2RB, IL5RB)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP FC
CD131, also known as the IL-3R common B subunit (BC), is a 95-120kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common B subunit associates with the specific a subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. This antibody is a non-Blocking antibody.
Catalog #I7663-48L
ApplicationsSuitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 0.5ug/10e5 cells in 100ul
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1, k
Clone No1C1
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman IL-3R B chain transfected COS cells
SpecificityRecognizes human CD131.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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