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Anti -Interleukin 1 Receptor Antagonist (IL-1RA)
Anti -Interleukin 1 Receptor Antagonist (IL-1RA)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH |
|
| The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. | | | Catalog # | I7663-61 | | Applications | Suitable for use in Immunohistochemistry, ELISA and Chemiluminescent Immuno Assay (CLIA). Other applications not tested. | | Recommended Dilution | Immunohistochemistry: Frozen | | ELISA: 20-2000pg/ml | | CLIA: 0.050-15ng/ml | | Optimal dilution to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 4H145 | | Host | Mouse | | Source | Human | | Concentration | 1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Human IL-1RA | | Specificity | Recognizes both the recombinant and the natural form of human IL-1RA. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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