Interleukin 4, Recombinant, Mouse (IL-4, B Cell Stimulatory Factor 1, BSF1, Binetrakin,
HCGF, Hodgkin's Cell Growth Factor, IA Inducing Factor, Lymphocyte Stimulatory Factor 1,
Macrophage Fusion Factor, Mast Cell Growth Factor 2, MCGF2, MFF, MGC79402, Pit
Pricing
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| IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5kD globular protein containing 120 amino acid residues. | | | Catalog # | I8426-10C | | Source | Escherichia coli. | | Biological Activity | The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is 2.0ng/ml, corresponding to a specific activity of 5x105e units/mg. | | Endotoxin | 1EU/ug (LAL) | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 1 month at 4 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~13.5kD | | Source | E. coli | | Purity | 95% as determined by SDS-PAGE and HPLC. | | Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 50ug of HSA per 1ug of cytokine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Interleukin 4, Recombinant, Mouse (IL-4, B Cell Stimulatory Factor 1, BSF1, Binetrakin, HCGF, Hodgkin's Cell Growth Factor, IA Inducing Factor, Lymphocyte Stimulatory Factor 1, Macrophage Fusion Factor, Mast Cell Growth Factor 2, MCGF2, MFF, MGC79402, Pit |
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