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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 6, Recombinant, Mouse (IL-6)

Interleukin 6, Recombinant, Mouse (IL-6)

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Specifications

Interleukin (IL)-6 is an important proinflammatory and immunoregulatory cytokine expressed by various cells.Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.
Catalog #I8428-10C
Biological Activity Recombinant Murine IL-6 is fully biologically active when compared to standard. The ED50 determined by the dose-dependent induction of 7TD1 cell proliferation is 0.018ng/ml.
AA SequenceMFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with 10mM HCl and a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight21.7kD
SourceRecombinant, murine, E. coli
Purity>95% as determined by reducing and non-reducing SDS-PAGE.
FormSupplied as a lyophilized powder. Reconstitute with 10mM HCl to 0.1-1mg/ml, and a carrier protein (0.1% HSA or BSA).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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