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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 6, Recombinant, Rat (IL-6)

Interleukin 6, Recombinant, Rat (IL-6)

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Specifications

Interleukin (IL)-6 is an important proinflammatory and immunoregulatory cytokine expressed by various cells.has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.
Catalog #I8428-15C
Biological Activity Recombinant Rat IL-6 is fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of murine 7TD1 cells is < 0.01ng/ml, corresponding to a Specific Activity of 1x108 IU/mg.
AA SequenceMFPTSQVRRG DFTEDTTHNR PVYTTSQVGG LITYVLREIF EMRKELCNGN SDCMNSDDAL SENNLKLPEI QRNDGCFQTG YNQEICLLKI CSGLLEFRFY LEFVKNNLQD NKKDKARVIQ SNTETLVHIF KQEIKDSYKI VLPTPTSNAL LMEKLESQKE WLRTKTIQLI LKALEEFLKV TMRSTRQT
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight21.8kD
Purity~95% Analysis by RP-HPLC; Reducing and non-reducing SDS-PAGE.
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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