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Anti -IL6 (Interleukin-6, Interleukin 6, B-cell Hybridoma Growth Factor, Interleukin HP-1, Il6, Il-6)
Anti -IL6 (Interleukin-6, Interleukin 6, B-cell Hybridoma Growth Factor, Interleukin HP-1,
Il6, Il-6)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E |
|
| Interleukin 6 (IL-6) is a 21kD multifunctional protein 212aa in length that plays critical roles in host defense, immune response, and hematopoiesis. IL-6 is constitutively expressed by epidermal Langerhans cells that its expression is induced in stimulated keratinocytes. IL-6, IL-1, and TNF, acts as endogenous pyrogens, regulating the fever response to bacterial invasion. IL-6 has been shown to activate the Ras/MAP kinase pathway, which regulates NF-IL-6 transcription. | | | Catalog # | I8428-31K | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Positive Control | Mouse IL-6 recombinant protein. Mouse heart. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Clone No | 2D46 | | Host | Rat | | Source | Mouse | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to mouse IL-6. | | Specificity | Recognizes mouse IL6. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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