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You are here:Home » Molecular Biology » MB-Growth Factors-Interleukin » Interleukin 6 Receptor, soluble, Recombinant, Human (IL6-sR)

Interleukin 6 Receptor, soluble, Recombinant, Human (IL6-sR)


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Recombinant IL6-sR comprises a 161 amino acid fragment (aa20-357) corresponding to the mature IL6-sR protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
The IL-6 receptor complex is composed of two membrane glycoproteins: the low affinity receptor and the signal- transducing component. The soluble form of IL6R is found in the urine of healthy adult humans and the serum of HIV positive individuals, as well as in the cell culture supernatants of stimulated PBMC’s. This soluble form of IL6R results from either proteolytic cleavage from the membrane, or an isoform derived splice variant.
Catalog #I8428-40A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended Dilutions:
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight42.25kD
SourceE. coli
ConcentrationAs reported
FormSupplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.8M urea, 50% glycerol
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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