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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)

Anti -Interleukin 10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH
Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non-glycosylated polypeptide consisting of 160 amino acids. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines, and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells, and thymocytes.
Catalog #I8432-01
ApplicationsSuitable for use in ELISA and immunohistochemistry. Other applications have not been tested.
Recommended DilutionImmunohistochemistry (Frozen): 10-20ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlTonsil tissue
HybridomaBALB/c mouse spleen cells were fused with SP/20 mouse myeloma cells.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No5J47
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.5, 0.05% sodium azide.
PurityPurified by Protein A affinity column chromatography.
ImmunogenPurified recombinant human IL-10
SpecificityRecognizes natural and recombinant human IL-10. Cross-reactivity: Epstein-Barr viral IL-10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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