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Anti -Interleukin 10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)
Anti -Interleukin 10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E |
|
| Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. The reported biological activities of IL-10, which may be interrelated, include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed-type hypersensitivity response, and stimulation of the Th2 cell response which results in elevated antibody production. Human IL-10 is active on murine cells. Murine IL-10 is inactive on human cells. Recombinant human IL-10 is an 18.6kD protein with 161 amino acid residues. | | | Catalog # | I8432-01F | | Application | Suitable for use in ELISA as a capture antibody. Other applications have not been tested. | | Recommended Dilutions | | | ELISA: 1-5ug/ml; Coat each well with 100ul. | | Optimal dilutions to be determined by the researcher. | | Recommended Pair | Suitable for use as the capture or solid phase antibody. | | Matched to I8432-16 as the detection or conjugate (label) antibody. | | Hybridoma | BALB/c splenocytes were fused with NSO mouse myeloma cells. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 5J48 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.5, 0.05% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Human Interleukin 10 | | Specificity | Recognizes natural and recombinant human IL-10. Binds to epitope B of the IL-10 protein and is non-neutralizing. Does not bind to the Epstein Barr viral IL-10. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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