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Anti -Interleukin 10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)
Anti -Interleukin 10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Highly Purified |
E B |
|
| Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non-glycosylated polypeptide consisting of 160 amino acids. There is 73% homology between the human and mouse IL10 proteins, However, human IL10 acts on both human and mouse target cells, while mouse IL10 has species-specific activity. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines, and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells, and thymocytes. | | | Catalog # | I8432-13M | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 8A187 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 40% glycerol. | | Purity | Purified by ion exchange chromatography. | | Immunogen | Recombinant human IL-10 | | Specificity | Recognizes human IL-10. Species sequence homology: Mouse 73%. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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