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Interleukin 12, p40, Recombinant, Human (IL-12)
Interleukin 12, p40, Recombinant, Human (IL-12)
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| Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23. Recombinant human IL-12 p40 is a 40kD protein containing 306 amino acid residues. | | | Catalog # | I8434-31B | | Stability | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -200C. Reconstituted IL-12 p40 should be stored in working aliquots at -200C. | | Purity | 95% by SDS-PAGE and HPLC analyses. | | Endotoxin | 0.1ng per ug (1EU/ug). | | Biological Activity | Not available | | AA Sequence | p40-Sub unit --IWELKKDV YVVELDWYPD APGEMVVLTC DTPEEDGITW TLDQSSEVLG SGKTLTIQVK EFGDAGQYTC HKGGEVLSHS LLLLHKKEDG IWSTDILKDQ KEPKNKTFLR CEAKNYSGRF TCWWLTTIST DLTFSVKSSR GSSDPQGVTC GAATLSAERV RGDNKEYEYS VECQEDSACP AAEESLPIEV MVDAVHKLKY ENYTSSFFIR DIIKPDPPKN LQLKPLKNSR QVEVSWEYPD TWSTPHSYFS LTFCVQVQGK SKREKKDRVF TDKTSATVIC RKNASISVRA QDRYYSSSWS EWASVPCS | | Country of Origin | USA | | Source | CHO cells (Chinese Hamster Ovarian cells) | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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