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You are here:Home » Molecular Biology » MB-Growth Factors-Interleukin » Interleukin 12, p40, Recombinant, Human (IL-12)

Interleukin 12, p40, Recombinant, Human (IL-12)


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Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23. Recombinant human IL-12 p40 is a 40kD protein containing 306 amino acid residues (23-328).
Catalog #I8434-31B1
Endotoxin 0.1ng per ug (1EU/ug)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Molecular Weight40kD
SourceE. coli
Purity95% by SDS-PAGE and HPLC analyses
FormSupplied as a sterile-filtered and lyophilized powder. Reconstitute in 1X PBS, pH 7.2 to a concentration of 0.1-1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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