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You are here:Home » Antibodies » Antibodies-Interleukin » Anti -Interleukin 13 (IL-13)

Anti -Interleukin 13 (IL-13)


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Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B IH N
IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-in ammatory effects on monocytes and macrophages. It also induces B cells to proliferate and isotype-switch to the production of IgE. In addition, IL-13 modulates TH2 cell development interfering key roles in the ostracizing of gastrointestinal parasites and in the evolvement of asthma and allergy.
Catalog #I8435-05
ApplicationsSuitable for use in Neutralizing, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 5ug/ml. Detects 100ng of human IL-13
Immunohistochemistry: Frozen sections
Note: Further dilutions should be made in in medium or buffered solutions with a carrier protein such as 1% BSA.
Optimal dilutions to be determined by researcher.
HybridomaRat spleen cells fused with P3X63-AG8.653 myeloma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No1.B2.1
FormSupplied as a liquid in PBS.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenPurified recombinant human IL-13
SpecificityRecognizes natural and recombinant human IL-13.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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