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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 13 (IL-13)

Anti -Interleukin 13 (IL-13)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B IH N
IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-in ammatory effects on monocytes and macrophages. It also induces B cells to proliferate and isotype-switch to the production of IgE. In addition, IL-13 modulates TH2 cell development interfering key roles in the ostracizing of gastrointestinal parasites and in the evolvement of asthma and allergy.
Catalog #I8435-05
ApplicationsSuitable for use in Neutralizing, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 5ug/ml. Detects 100ng of human IL-13
Immunohistochemistry: Frozen sections
Note: Further dilutions should be made in in medium or buffered solutions with a carrier protein such as 1% BSA.
Optimal dilutions to be determined by researcher.
HybridomaRat spleen cells fused with P3X63-AG8.653 myeloma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No1.B2.1
HostRat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenPurified recombinant human IL-13
SpecificityRecognizes natural and recombinant human IL-13.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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