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Interleukin 15, Recombinant, Human (IL-15)
Interleukin 15, Recombinant, Human (IL-15)
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| IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant human IL-15 is a 13.2 kDa protein consisting of the following 114 amino acid residues. | | | Catalog # | I8437-01F | | Source | Escherichia coli. | | Biological Activity | Measured in a cell proliferation assay using CTLL-2 cells, the specific activity shall be not less than 2 x 10e6 units/mg. | | Endotoxin | 1EU/ug (LAL) | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 1 month at 4 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~13.2kD | | Source | E. coli | | Purity | 97% as determined by SDS-PAGE and HPLC. | | Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 50ug of HSA per 1ug of cytokine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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