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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 15, Recombinant, Human (IL-15)

Interleukin 15, Recombinant, Human (IL-15)

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Specifications

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant human IL-15 is a 13.2 kDa protein consisting of the following 114 amino acid residues.
Catalog #I8437-01F
SourceEscherichia coli.
Biological ActivityMeasured in a cell proliferation assay using CTLL-2 cells, the specific activity shall be not less than 2 x 10e6 units/mg.
Endotoxin 1EU/ug (LAL)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 6 months at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 1 month at 4 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~13.2kD
SourceE. coli
Purity97% as determined by SDS-PAGE and HPLC.
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 50ug of HSA per 1ug of cytokine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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