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Interleukin 15, Recombinant, Mouse (IL-15)
Interleukin 15, Recombinant, Mouse (IL-15)
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| IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant murine IL-15 is a 13.3kD protein consisting of 115 amino acid residues. | | | Catalog # | I8437-05 | | Biological Activity | The ED50 was determined by the stimulation of the proliferation of murine CTLL-2 cells is 5ng/ml, corresponding to a specific activity of 2x10e5 units/mg. | | AA Sequence | MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitutewith sterile ddH2O. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Source | Recombinant, Murine (E. coli | | Purity | ~ 98%, SDS-PAGE, HPLC. Endotoxin: 0.1ng/ug (1EU/ug) | | Form | Supplied as a lyophilized powder. Reconstitute with sterile dH2O. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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