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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 15, Recombinant, Mouse (IL-15)

Interleukin 15, Recombinant, Mouse (IL-15)

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Specifications

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant murine IL-15 is a 13.3kD protein consisting of 115 amino acid residues.
Catalog #I8437-05
Biological Activity The ED50 was determined by the stimulation of the proliferation of murine CTLL-2 cells is 5ng/ml, corresponding to a specific activity of  2x10e5 units/mg.
AA Sequence MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitutewith sterile ddH2O. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceRecombinant, Murine (E. coli
Purity~ 98%, SDS-PAGE, HPLC. Endotoxin: 0.1ng/ug (1EU/ug)
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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