You are here:Home
»
Growth Factors, Cytokines
»
Growth Factors-Interleukin
»
Interleukin 16, Recombinant, Mouse (IL-16)
Interleukin 16, Recombinant, Mouse (IL-16)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Recombinant Murine IL-16 is a proinflammatory cytokine inducing immunomodulatory effects of CD41 lymphocytes, monocytes, and eosinophils via CD4. Comparative analysis of murine and human IL-16 show a high degree of amino acid similarity. The highest similarity (82.1%) was found in the C-terminal region. Chemotaxis experiments with IL-16 of murine and human origin, using murine splenocytes or human T lymphocytes as targets, showed cross-species motility. There is a high degree of structural and functional similarity between human and murine IL-16. Murine IL-16 is comprised of 127 amino acids, with a molecular weight of 13.2kD. | | | Catalog # | I8437-07B | | Biological Activity | Recombinant mouse IL-16 has full biologicial activity compared to a standard. The activity, determined by dose-dependent chemoattraction of lprimary human T cells, is detectable at ~5ng/ml | | AA Sequence | MHDLNSSTDS AASASAASDI SVESKEATVC TVTLEKTSAG LGFSLEGGKG SLHGDKPLTI NRIFKGDRTG EMVQPGDEIL QLAGTAVQGL TRFEAWNVIK ALPDGPVTIV IRRTSLQCKQ TTASADS | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 13.2kD | | Source | E. coli | | Purity | 95% as determined by reducing and non-reducing SDS-PAGE. | | Form | Supplied as a lyophilized powder. Reconstitute with sterile dH2O to 0.1mg/ml. For long term storage add 0.1% BSA or HSA. Further dilution can be made in other aqueous solutions. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
